Axoguard Nerve Protector®
Axoguard Nerve Protector is the only small intestine submucosa (SIS) implant designed to protect injured and compressed nerves up to 40 mm.
protector innovations
- Provides a protective barrier to separate the nerve from the surrounding tissues.1
- Minimizes the potential for soft tissue attachments to allow the nerve to glide.1
- Vascularizes and remodels into the patient’s own tissue.1
- Available in a variety of lengths and diameters for intra-operative versatility.
- to order, obtain more information or report adverse events
contact axogen customer care: - Phone
888.axogen1 (888.296.4361) - Email
customercare@axogenInc.com - see sizing info below
In a pre-clinical study conducted to evaluate host tissue response, porcine small intestine submucosa (SIS, Axoguard Nerve Connector) performed significantly better than cross-linked bovine collagen type I (CLC, Integra NeuraGen®) in all outcomes and categories.
Specifically, the study provided evidence that SIS had increased levels of M2 (pro-healing) macrophages which are indicative of a remodeling response, while CLC had increased levels of M1 (pro-inflammatory) macrophages indicative of a chronic inflammatory response.2,3
M1 and M2 Macrophage Distribution
Host Response
#1
U.S. market leader*
in off-the-shelf nerve reconstruction solutions.
*IQVIA U.S. market data
6 mos
to remodel into protective layer.1
remodels and vascularizes
to minimize potential for soft tissue attachments.
INDICATIONS FOR USE: Axoguard Nerve Protector is indicated for the repair of peripheral nerve injuries where there is no gap. The device is supplied sterile and is intended for one-time use.
CONTRAINDICATIONS: This device is derived from porcine source and should not be used for patients with known sensitivity to porcine material.
| Code | Dimensions |
| AG0220 | 2 mm x 20 mm |
| AG0320 | 3.5 mm x 20 mm |
| AG0520 | 5 mm x 20 mm |
| AG0720 | 7 mm x 20 mm |
| AG1020 | 10 mm x 20 mm |
| Code | Dimensions |
| AG0340 | 3.5 mm x 40 mm |
| AG0540 | 5 mm x 40 mm |
| AG0740 | 7 mm x 40 mm |
| AG1040 | 10 mm x 40 mm |
