AxoGuard® Nerve Protector

AxoGuard® Nerve Protector, is the only  porcine submucosa extracellular (ECM) matrix surgical implant used to  protect injured nerves and to reinforce the nerve reconstruction while preventing soft tissue attachments. Designed to protect and isolate, the AxoGuard® multi-laminar ECM  separates and protects the nerve from the surrounding tissues during the healing process. The patient’s own cells incorporate into the minimally processed extracellular matrix to remodel and form a tissue similar to the nerve epineurium. AxoGuard® Nerve Protector is provided sterile and in a variety of sizes to meet the surgeon’s and anatomical needs.

AxoGuard® Nerve Protector can be used to:

    • Protect injured nerves up to 40mm
    • Minimize risk of entrapment in compressed nerves
    • Protect partially severed nerves
    • Reinforce a coaptation site

AxoGuard® Nerve Protector has the following key advantages:

    • Minimizes the potential for soft tissue attachments and nerve entrapment by physically isolating the nerve during the healing process1,2
    • Preserves the native architecture of the extracellular matrix
    • Allows nerve gliding1,2
    • Strong and flexible, plus easy to suture
    • Stored at room temperature with an 18 month shelf life.


AxoGen strives to broaden the research and knowledge base of peripheral nerve injury and repair by identifying what factors “matter” in nerve repair.  The link below provides information about how processing may affect nerve repair.
AxoGuard® Nerve Protector: Processing Matters


The AxoGuard® Nerve Protector is indicated for the repair of peripheral nerve injuries where there is no gap. The device is supplied sterile and is intended for one-time use.

This device is derived from porcine source and should not be used for patients with known sensitivity to porcine material.

1. Xu, et al. 2000, J Hand Surg [Am] 25(1):93-103.
2. Data on file at AxoGen, Inc.