Our Clinical Research

AxoGen invests in and supports clinical studies and programs to further the understanding and outcomes of peripheral nerve repair.



A Multicenter, Retrospective Study of Avance® Nerve Graft Utilization, Evaluations and Outcomes in Peripheral Nerve Injury Repair (RANGER®). The RANGER® Study, the Avance® Nerve Graft Registry, has completed the first data milestone and continues to enroll additional cases. 



A Multicenter, Prospective, Randomized, Comparative Study of Hollow Nerve Conduit and Avance® Nerve Graft Evaluation Recovery Outcomes of the Nerve Repair in the Hand (CHANGE). The CHANGE Study is a pilot comparative study. Enrollment is now completed.


A Multicenter, Prospective, Randomized, Subject and Evaluator Blinded Comparative Study of Nerve Cuffs and Avance® NerveGraft Evaluating Recovery Outcomes for the Repair of Nerve Discontinuities (RECON). The primary objective of this study is to evaluate the difference in functional recovery outcome between the study groups.


ANG-CP-003: Cavernous Nerve Reconstruction Using Avance® Nerve Graft in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer. This study is being conducted to assess the technical feasibility of robotic assisted implantation of Avance® Nerve Graft and the long term outcomes for continence and potency in men undergoing radical prostatectomy. Enrollment is now completed.


For inquiries or to request additional information about AxoGen’s Clinical Research Program, click here.